AstraZeneca's Doctor Paid Speaker Dream Team - CIA Disclosure Time

AstraZeneca's Doctor Paid Speaker Dream Team - CIA Disclosure Time

The following is a listing of doctors who have received compensation as paid AstraZeneca Shills
Pimps Whores speakers. This listing and information is not from the ProPublica Dollars for Docs database
;which is another excellent source to check to see how much bounty money your doctor may be hoarding away secretly accepting from the pharmaceutical industry.

Conflicts of Interest is a huge & shameful problem in medicine as a whole, @ the FDA, @ the NIH, @ the CDC, in research, clinical trials, professional journals, scholastic institutions, and general medical practices today that has lead to an epidemic of shoddy science and dangerous products reaching you the patient victim patsy public at alarming levels of frequency and regularity.

As we can see with this seroquel litigation and many other similar organized assaults crimes against patients: medicine and physicians cannot serve two masters concurrently: we as a nation & consumers must make doctors choose to either serve those they have sworn an oath to serve "Patients", or to serve those greedy drug cartels corporations filling their pockets and bank accounts full of cold hard cash instead.

So without further ado, let us open the pdf envelopes linked below and see the doctors who have received their notorious $award$ status.

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astrazeneca-us.com/responsibility/transparency/cia
The reports below disclose compensation AstraZeneca has paid to all US-based physicians who spoke on behalf of AstraZeneca and/or its products during 2010. The company announced its decision to disclose these payments in May 2009. In addition, reporting this information twice a year, is now part of the Company’s April 2010 Corporate Integrity Agreement with the Office of Inspector General, and will be a requirement under the Physician Payment Sunshine provisions in the Patient Protection and Affordable Care Act. AstraZeneca will report compensation to physicians biannually for 2010 and quarterly beginning in 2011.

2011

•  Speaker Compensation Report (January-March 2011) 

2010

•  Speaker compensation report (January - June 2010)
•  Speaker compensation report (July - December 2010)

CORPORATE INTEGRITY AGREEMENT BETWEEN THE OFFICE OF INSPECTOR GENERAL OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES AND ASTRAZENECA PHARMACEUTICALS LP AND ASTRAZENECA LP

Seroquel Lawsuit - Are Plaintiff Law Firms working in their clients (injured parties) best interest or just their own?

Seroquel Lawsuit - Are Plaintiff Law Firms working in their clients (injured parties) best interest or just their own - The question of ethical legal practice!



This morning Pharmalot Web site posted an interview with NPR reporter Snigdha Prakash who gives a stunning glimpse inside the legal tort system & how it works with these large pharmaceutical backroom settlement wheeling and dealings . I have suspected for sometime that plaintiff law firms in the seroquel litigation that have consistently shown a subversive lack of interest in their clients cases, questions, and inquirers were not passing the smell test.  Now with this revealing interview & book we get a better picture of what is being hidden from injured parties in the seroquel litigation & the serious ethical breeches that maybe occurring.

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from pharmalot - merck-vioxx-and-the-legal-system-author snigdha-explains/

In a new book, ‘All The Justice Money Can Buy,’ former National Public Radio reporter Snigdha Prakash, who was embedded with a team of plaintiffs’ lawyers for one of those trials, describes legal machinations, strategies and battles that eventually led Merck to reach a $5 billion settlement (see here). Along the way, she encounters a raft of outsized personalities - notably, plaintiff’s lawyer Mark Lanier and expert witness David Egilman - as she opens a window into the behind-the-scenes working of product-liability litigation and what it can mean for the ordinary patient.


Pharmalot: In your view, what was the most compelling take away from this whole episode?

Prakash: I think what really shocked me was the extent of the scientific manipulation. It had never occurred to me, and it’s probably quite naïve. I knew the tobacco industry played with science and I knew about accounting and financial fraud, because I had been a banking reporter. I understood about cooking numbers. But I didn’t understand about manipulating clinical trial data and couldn’t believe a company of Merck’s stature could be doing that. …I turned to epidemiologists and cardiologists and asked all these questions that a reporter asks. All these stupid questions. And I kept coming up against the fact that this very big company was really not treating people and human lives in the way you would expect them to. And you look around at the cultural and social landscape and you see, well, what I learned from covering litigation and trials before that is how hard it is to hold powerful corporate actors to account.


And it’s not just Merck and it’s not just the drug industry. It’s the financial industry. People lost their houses. People who invested their savings in their houses… There’s a common theme – a failure of government regulation. I think the theme I kept coming up against is that these were powerful actors and consumers trusted them. We think the government has our back. And we think if something goes wrong, the courts will come in and save us and protect us. In the case of pharmaceuticals, there are experts, doctors, who know what’s going on. But you’re out there by yourself. And it’s very hard to go after wrongdoing and make it right.

Pharmalot: What’s your take on the willingness and ability of the plaintiffs’ lawyers to come through for those who say there were harmed?

Prakash: Like any other group, they come in all shapes and sizes. Some of have different scruples and play different roles in the plaintiffs’ bar. Some collect cases and build inventories (of cases), although they don’t like to call it that. It’s clear that not all of these cases can be tried. But what do you with the cases? Everyone is interested in getting to the end game, which is clearing the dockets for judges. For Merck, it’s to make the mass tort go away. And for the plaintiffs’ lawyers, it’s to see a return from their investment, which can very large but takes a lot of money to go up against a big corporation. Their spending a pittance of what Merck spent, but it’s still real money.

What I walked away with is that it’s a business. At the end of the day, plaintiffs’ lawyers are pursuing their business interests and you have to hope their interests are aligned with yours as a plaintiff. Sometimes they are and sometimes they aren’t. Legal ethicists had problems with settlement terms. To receive a share, lawyers had to bring every single client along. I know they don’t like this formulation and so they effectively fired each client if they don’t come along

(read more here).

Pharmalot: Where are the weaknesses in this deal?

Zipursky: For one, look at the stipulation that says lawyers have to recommend this to their clients. They’re obligated to push the settlement. That conflicts with the obligation to do what’s best for the client. Why does this matter? Well, different people find different ways to go to court and challenge the validity of a settlement. Usually, that would be easier in a class action, and this isn’t a class action. But something that has a legally questionable provision can turn out to be a problem for everyone who is party to the agreement.

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Now we don't know for sure at this juncture if the law firms in the Seroquel litigation have made this same type of backroom deal with AstraZeneca. What I do know is that I've been told this is a take or leave it settlement offer of an undisclosed amount & the law firms will not give out any more information than that, except endless drivel of misinformation about when the offer packets will be sent out (the dark secret).

We also know that many (if not all) involved law firms have either washed their web sites of seroquel information & updates, or placed notice they are no longer accepting Seroquel cases (was that move also part of the secret deal?).

These actions & the personal disinterest in clients concerns and inquiry no doubt leads to strong suspicions that these legal firms are looking out for their own financial and business interest first & foremost; which pretty much flies in the face of their professional, ethical, and legal obligation to represent their clients best interest.

Some might even construe these actions as constituting legal malpractice or worse yet FRAUD?

Feel free to leave a comment on this topic...in fact if there are any morally ethical and responsible law firms or attorney groups interesting in taking on seroquel litigants/cases once they have been thrown to the curb by their current representation, please leave your contact information....

Seroquel (quetiapine) is an antipsychotic, a neuroleptic--NOT an antidepressant --get to know the fine print side effects of the medicine you take

                                                     ** photo credit hat-tip to pharmagossip blog **

The first question you need to be asking: if you're not psychotic, why would anyone prescribe you an antipsychotic? Of course we know the answer to this question; AstraZeneca is bound and determined (your health be damned) to market Seroquel & SeroquelXR for every billion they can...

The second Question you should be asking: How did a dangerous and powerful anti-psychotic (neuroleptic) become one of the most prescribed drugs on the planet?...it's not like we have had a sudden pandemic of psychosis grapple the planet earth...

The final question that must be asked & answered: Do the benefits significantly outweigh the risk with seroquel?

I want you to take a serious look at the side effects listed below...now take to heart that Seroquel has shown to be no better, less harmful, or any more effective than the old non-atypical anti-psychotics like haldol etc....Should anyone take a drug that has elevated risk of serious and permanently debilitating consequences for a mental health condition that has no known/proven origin or pathology.

The prescribing information addresses suicidal thinking yet call it a side effect of antidepressants (true) why not call it an antipsychotic? Could it be the marketing re-packaging PR department? This drug is being watered down to the point of general use where the next thing we hear is it is a common anti-anxiety drug...oh wait, that already happened with off-label prescriptions.

BE AWARE OF THIS DRUG, READ THE FINE PRINT. ESPECIALLY IF YOU'VE BEEN PRESCRIBED OFF-LABEL FOR INSOMNIA OR ANXIETY. MANY PCP'S RX SEROQUEL FOR THOSE REASONS AND ONE MAY NOT RECEIVE PROPER INFORMED CONSENT. START HERE.KNOW THE PRODUCT YOU BOUGHT.

AstraZeneca-Seroquel prescribing information sheet:

SEROQUEL (SER-oh-kwell) (quetiapine fumarate) Tablets Read this Medication Guide before you start taking SEROQUEL and each time you get a refill. There may be new information. This Medication Guide does not take the place of talking to your healthcare provider about your medical condition or treatment.

What is the most important information I should know about SEROQUEL?

Serious side effects may happen when you take SEROQUEL, including:

 • Risk of death in the elderly with dementia: Medicines like SEROQUEL can raise the risk of death in elderly people who have lost touch with reality due to confusion and memory loss (dementia). SEROQUEL is not approved for treating psychosis in the elderly with dementia.

• Risk of suicidal thoughts or actions: Antidepressant medicines, depression and other serious mental illnesses, and suicidal thoughts or actions:

1. Antidepressant medicines may increase suicidal thoughts or actions in some children, teenagers, and young adults within the first few months of treatment.
2. Depression and other serious mental illnesses are the most important causes of suicidal thoughts and actions. Some people may have a particularly high risk of having suicidal thoughts or actions. These include people who have (or have a family history of) depression, bipolar illness (also called manic-depressive illness), or suicidal thoughts or actions.
3. How can I watch for and try to prevent suicidal thoughts and actions in myself or a family member? • Pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings. This is very important when an antidepressant medicine is started or when the dose is changed. • Call the healthcare provider right away to report new or sudden changes in mood, behavior, thoughts, or feelings. • Keep all follow-up visits with the healthcare provider as scheduled. Call the healthcare provider between visits as needed, especially if you have concerns about symptoms.

Call a healthcare provider right away if you or your family member has any of the following symptoms, especially if they are new, worse, or worry you: • thoughts about suicide or dying • attempts to commit suicide • new or worse depression • new or worse anxiety • feeling very agitated or restless.

• panic attacks • trouble sleeping (insomnia) • new or worse irritability • acting aggressive, being angry, or violent • acting on dangerous impulses • an extreme increase in activity and talking (mania)
• other unusual changes in behavior or mood

What else do I need to know about antidepressant medicines?

(antidepressants are Celexa,Prozac, Lexapro,Cymbalta, Zoloft, etc)

• Never stop an antidepressant medicine without first talking to your healthcare provider. Stopping an antidepressant medicine suddenly can cause other symptoms.
 • Antidepressants are medicines used to treat depression and other illnesses. It is important to discuss all the risks of treating depression and also the risks of not treating it. Patients and their families or other caregivers should discuss all treatment choices with the healthcare provider, not just the use of antidepressants. • Antidepressant medicines have other side effects. Talk to the healthcare provider about the side effects of the medicine prescribed for you or your family member.

• Antidepressant medicines can interact with other medicines. Know all of the medicines that you or your family member take. Keep a list of all medicines to show the healthcare provider. Do not start new medicines without first checking with your healthcare provider.

• Not all antidepressant medicines prescribed for children are FDA approved for use in children. Talk to your child’s healthcare provider for more information.

What is SEROQUEL?

• SEROQUEL is a prescription medicine used to treat schizophrenia in people age 13 or older.

 • SEROQUEL is a prescription medicine used to treat bipolar disorder, including: • depressive episodes associated with bipolar disorder in adults

 • manic episodes associated with bipolar I disorder alone or with lithium or divalproex in adults • long-term treatment of bipolar I disorder with lithium or divalproex in adults

 • SEROQUEL is used to treat manic episodes associated with bipolar I disorder in children ages 10 to 17 years. SEROQUEL has not been studied in patients younger than 10 years of age.

What should I tell my healthcare provider before taking SEROQUEL?

 Before taking SEROQUEL, tell your healthcare provider if you have or have had:

• diabetes or high blood sugar in you or your family: your healthcare provider should check your blood sugar before you start SEROQUEL and also during therapy.

 • high levels of total cholesterol, triglycerides or LDL-cholesterol or low levels of HDL- cholesterol • low or high blood pressure.

• low white blood cell count

• cataracts

 • seizures

 • abnormal thyroid tests

 • high prolactin levels

 • heart problems

 • liver problems

• any other medical condition

• pregnancy or plans to become pregnant. It is not known if SEROQUEL will harm your unborn baby.

 • breast-feeding or plans to breast-feed. It is not known if SEROQUEL will pass into your breast milk. You and your healthcare provider should decide if you will take SEROQUEL or breast-feed. You should not do both. Tell the healthcare provider about all the medicines that you take or recently have taken including prescription medicines, non-prescription medicines, herbal supplements and vitamins. SEROQUEL and other medicines may affect each other causing serious side effects.

SEROQUEL may affect the way other medicines work, and other medicines may affect how SEROQUEL works. Especially tell your healthcare provider if you take or plan to take medicines for:

 • depression • high blood pressure • Parkinson’s disease • trouble sleeping Also tell your healthcare provider if you take or plan to take any of these medicines:

• phenytoin, divalproex or carbamazepine (for epilepsy) • barbiturates (to help you sleep) • rifampin (for tuberculosis) • glucocorticoids (steroids for inflammation) • thioridazine (an antipsychotic) • ketoconazole, fluconazole or itraconazole (for fungal infections) • erythromycin (an antibiotic) • protease inhibitors (for HIV)

This is not a complete list of medicines that can affect or be affected by SEROQUEL. Your doctor can tell you if it is safe to take SEROQUEL with your other medicines. Do not start or stop any medicines while taking SEROQUEL without talking to your healthcare provider first. Know the medicines you take. Keep a list of your medicines to show your healthcare provider and pharmacist when you get a new medicine.

How should I take SEROQUEL? • Take SEROQUEL exactly as your healthcare provider tells you to take it. Do not change the dose yourself. • Take SEROQUEL by mouth, with or without food. • If you feel you need to stop SEROQUEL, talk with your healthcare provider first.

If you suddenly stop taking SEROQUEL, you may experience side effects such as trouble sleeping or trouble staying asleep (insomnia), nausea, and vomiting.

 • If you miss a dose, take it as soon as you remember. If it is close to the next dose, skip the missed dose. Just take the next dose at your regular time. Do not take 2 doses at the same time unless your healthcare provider tells you to. If you are not sure about your dosing, call your healthcare provider.

 • If you take too much SEROQUEL, call your healthcare provider or poison control center at 1-800-222-1212 right away or go to the nearest hospital emergency room.

What should I avoid while taking SEROQUEL?

Do not drive, operate machinery, or do other dangerous activities until you know how SEROQUEL affects you. SEROQUEL may make you drowsy.

• Avoid getting over-heated or dehydrated. o Do not over-exercise. o In hot weather, stay inside in a cool place if possible. o Stay out of the sun. Do not wear too much or heavy clothing. o Drink plenty of water. • Do not drink alcohol while taking SEROQUEL. It may make some side effects of SEROQUEL worse. What are possible side effects of SEROQUEL? Serious side effects have been reported with SEROQUEL including: Also, see “What is the most important information I should know about SEROQUEL?” at the beginning of this Medication Guide

• Neuroleptic malignant syndrome (NMS): Tell your healthcare provider right away if you have some or all of the following symptoms: high fever, stiff muscles, confusion, sweating, changes in pulse, heart rate, and blood pressure. These may be symptoms of a rare and serious condition that can lead to death. Stop SEROQUEL and call your healthcare provider right away.

• High blood sugar (hyperglycemia): Increases in blood sugar can happen in some people who take SEROQUEL. Extremely high blood sugar can lead to coma or death. If you have diabetes or risk factors for diabetes (such as being overweight or a family history of diabetes) your healthcare provider should check your blood sugar before you start SEROQUEL and during therapy. Call your healthcare provider if you have any of these symptoms of high blood sugar while taking SEROQUEL:

• feel very thirsty • need to urinate more than usual • feel very hungry • feel weak or tired

• feel sick to your stomach • feel confused, or your breath smells fruity.

High cholesterol and triglyceride levels in the blood (fat in the blood) Increases in total cholesterol, triglycerides and LDL (bad) cholesterol and decreases in HDL (good) cholesterol have been reported in clinical trials with SEROQUEL. You may not have any symptoms, so your healthcare provider should do blood tests to check your cholesterol and triglyceride levels before you start taking SEROQUEL and during therapy.

• Increase in weight (weight gain): Weight gain has been seen in patients who take SEROQUEL so you and your healthcare provider should check your weight regularly.

• Tardive dyskinesia: Tell your healthcare provider about any movements you cannot control in your face, tongue, or other body parts. These may be signs of a serious condition. Tardive dyskinesia may not go away, even if you stop taking SEROQUEL. Tardive dyskinesia may also start after you stop taking SEROQUEL.

• Orthostatic hypotension (decreased blood pressure): lightheadedness or fainting caused by a sudden change in heart rate and blood pressure when rising too quickly from a sitting or lying position.

• Increases in blood pressure: reported in children and teenagers. Your healthcare provider should check blood pressure in children and adolescents before starting SEROQUEL and during therapy.

• Low white blood cell count

• Cataracts

• Seizures

• Abnormal thyroid tests: Your healthcare provider may do blood tests to check your thyroid hormone level.

• Increases in prolactin levels: Your healthcare provider may do blood tests to check your prolactin levels.

• Increases in liver enzymes: Your healthcare provider may do blood tests to check your liver enzyme levels.

• Long lasting and painful erection

• Difficulty swallowing

Common possible side effects with SEROQUEL include: Adults • drowsiness • upset stomach • dry mouth • weight gain • dizziness • a sudden drop in blood pressure • weakness upon standing • abdominal pain • abnormal liver tests • constipation • sore throat • sluggishness

Children and Adolescents:

• drowsiness •dizziness • fatigue •increased appetite • nausea •vomiting • dry mouth •rapid heart beat • weight gain These are not all the possible side effects of SEROQUEL.

For more information, ask your healthcare provider or pharmacist. Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

SEROQUEL IS AN ANTIPSYCHOTIC, along with others such as Zyprexa, Abilify, Haldol, Risperdal, Invega, Melleril and others.

Selling Our Children to the Pharmaceutical Industry - PBS reports

Selling Our Children to the Pharmaceutical Industry - PBS reports

Have we sold our kids to the pharmaceutical Industry? This PBS report appears to be evidence that foster kids have been not just used, but abused as cash cows for exactly this purpose...corrupted doctors who have forgotten they took an oath to do no harm, not to profit as much as possible. Medicine has lost it's way, and they are not going to change direction until we make them change direction. Watch this video and then read this supposed Sham  Torture study in 4 to 6 year old toddlers using seroquel. This is a precursory study leading to a much larger study planned in the future.
Yes, you could have guessed that it was directed out of Massachusetts General Hospital ( Janet Wozniak, MD ). Most in the know consider this Harvard University affiliated Hospital the center and birth place of the "BIPOLAR CHILD" Myth.

Please keep in mind as you read this study that there is no stated criteria for preschool bipolar disorder in the DSM-IV. The well funded Pharmaceutical Industry shill doctors @ Harvard created this criteria out of thin air to get drug approval from the FDA. Then using this witchcraft logic, come to the conclusion that the if the FDA approves the drug, then there must be a validated disease?

I have a really hard time following this sick and twisted bullshit logic that is putting thousands upon thousands of our children at dire risk; but I guess when billions of dollars in profits are at stake...Magic is made possible...

Watch the full episode. See more Need To Know.

http://clinicaltrials.gov/pediatric+quetiapine

 Quetiapine for Mania In Preschool Children 4 to 6 Years of Age With Bipolar Disorder

This study has been completed. 

 Purpose

This is an 8-week open-label study aimed at assessing the effectiveness and tolerability of Quetiapine, in the treatment of preschool children aged 4 to 6 years with bipolar and bipolar spectrum disorder. This is an exploratory, pilot study, seeking to determine whether Quetiapine is efficacious and well tolerated in the treatment of preschoolers with pediatric bipolar and bipolar spectrum disorder in this age group. The study results will be used to generate hypotheses for a larger randomized controlled clinical trial with explicit hypotheses and sufficient statistical power.

Official Title: Open-Label Study of Quetiapine for Mania In Preschool Children 4 to 6 Years of Age With Bipolar and Bipolar Spectrum Disorder

Primary Outcome Measures:

• reductions in symptoms measured by [ Time Frame: 8 weeks ] [ Designated as safety issue: No ]
  
• Young-Mania Rating Scale (Y-MRS) [ Time Frame: 8 weeks ] [ Designated as safety issue: No ]
  
• Mania Symptom Checklist [ Time Frame: 8 weeks ] [ Designated as safety issue: No ]
  

Estimated Enrollment:	20
Study Start Date:	February 2005
Study Completion Date:	April 2009
Primary Completion Date:	April 2009 (Final data collection date for primary outcome measure)

Intervention Details:

Drug: quetiapine (Seroquel)
2.5 - 5.0mg/kg PO BID quetiapine

Detailed Description:

Seroquel is a psychotropic agent that affects multiple neurotransmitter receptors in the brain: serotonin 5HT1A and 5HT2, dopamine D1 and D2, histamine H1 (IC50=30nM), and adrenergic receptors.

This is an 8-week open-label study aimed at assessing the effectiveness and tolerability of Quetiapine, in the treatment of preschool children aged 4 to 6 years with bipolar and bipolar spectrum disorder. This is an exploratory, pilot study, seeking to determine whether Quetiapine is efficacious and well tolerated in the treatment of preschoolers with pediatric bipolar and bipolar spectrum disorder in this age group. The study results will be used to generate hypotheses for a larger randomized controlled clinical trial with explicit hypotheses and sufficient statistical power.

  Eligibility

Ages Eligible for Study:	4 Years to 6 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

• Male or female subjects, 4-6 years of age.
• Subjects must have a DSM-IV diagnosis of bipolar I, bipolar II disorder or bipolar spectrum disorder and currently displaying manic, hypomanic, or mixed symptoms (with or without psychotic features) according to the DSM-IV based on clinical assessment and confirmed by structured diagnostic interview (Kidd Schedule of Affective Disorders and Schizophrenia Epidemiological Version). Bipolar spectrum disorder (or sub-threshold bipolar disorder) is operationalized as having severe mood disturbance, which meets DSM-IV Criteria A for bipolar disorder but meet fewer elements in criteria B (only require 2 items for elation category and 3 for irritability).
• Subjects and their legal representative must have a level of understanding sufficient to communicate intelligently with the investigator and study coordinator, and to cooperate with all tests and examinations required by the protocol.
• Subjects and their legal representative must be considered reliable.
• Each subject and his/her authorized legal representative must understand the nature of the study. The subject's authorized legal representative must sign an informed consent document.
• Subjects must have an initial score on the Y-MRS total score of at least 20.
• Subject must be able to participate in mandatory blood draws.
• Subjects with comorbid ADHD, ODD, CD, anxiety and depressive disorders will be allowed to participate in the study provided they do not meet for any of the exclusionary criteria.
• For concomitant stimulant therapy used to treat ADHD, subjects must have been on a stable dose of the medication for 1 month prior to study enrollment. The dose of the stimulant therapy will not change throughout the duration of the study.