Sunday, September 25, 2011

Bailey Perrin Bailey LLP- Over 6000 clients in AstraZeneca Seroquel Civil Litigation - Not a Single Trial - Now $$ Arkansas?

Bailey Perrin Bailey LLP - representing over 6000 injured clients in the Seroquel Litigation - jumps on a sleazy settlement - not a single trial? Yet, the State of Arkansas has hired them to go up against AstraZeneca at trial?

I thought it was about time to highlight one the other plaintiff heavy weights in the seroquel litigation Bailey Perrin Bailey LLP  out of Houston Texas (also known as Houston Associates) along with Weitz & Luxenberg P.C. . These law firms were deemed the lead plaintiff counsel (here page 4) in the Seroquel litigation together compiling over 8000 of the some 28000 injured party cases. From what I can gather reading questionable comments from some of their supposed clients in Topix Seroquel Lawsuit Forum; they are also settling for somewhere in the ball park of what W&L has.

What I find quite interesting is that Bailey Perrin Bailey is also co-counsel in the state of Arkansas  where AstraZeneca will be going to trial over the drug Seroquel in 2012 (Background here -> from the blog tmap & from bloomberg news ); and yet they have sold the injured parties they represent in the civil Seroquel litigation down the river in a settlement that will enrich BPB in the ball park of some 80 million dollars in profit , while leaving the injured parties with nothing more than a insulting token settlement in the very low thousands. On top of that action; to further add insult to injury, BPB will allow past, present, & future cost for the injured parties medical care to be heaped upon the government (Federal and States through Medicare, Medicaid, VA, Etc.) which is ultimately passed along to the American Tax Payer (that's you & me).

BPB has an estimated 6000+ Seroquel Cases and yet did not bring a single case to trial? Now they have been hired as co-counsel in the State of Arkansas to represent the public interest when they couldn't even represent the best interest of their own clients????

Something is very very wrong with this picture.......What percentage is BPB reaping in this deal with Arkansas? How many more millions of dollars will they gather up while those injured by Seroquel continue to suffer from the adverse effects, which include diabetes and related conditions (many of those forever mired down in abject poverty with substandard medical care) thanks to the so called representation of BPB.

Someone must begin to start questioning the ethics and professionalism being demonstrated in these kinds of seemingly reprehensible behaviors. Especially since BPB reached an agreement with AstraZeneca in the civil litigation to sell & market a low ball settlement offer to their clients, while still collecting for themselves in the neighborhood of 80 million dollars in profits..?

Not a bad deal for these sleazy ambulance chaser law firms...of course why not lose & screw over the injured party clients...the FDA is about to announce the next drug warning or questionable medical procedure that these law firms will be jumping up and down advertizing for new suckers to low ball swindle for another massive payday without ever having to take a case to trial...don't take my word for it...check out their web sites and TV commercials...then notice how their sites have been washed clean of Seroquel...?

Once again we can see here this is a huge WIN!! for (The Lawyers) even when they (The Lawyers) LOSE!! You start to wonder if Bailey Perrin Bailey and the majority of law firms involved in this litigation have any semblance of a moral consequence what so ever....

This also makes you start to wonder what other underhanded schemes the law firms may have been involved in...like just maybe recruiting past litigants they represented in the Zyprexa litigation & settlement into the Seroquel Litigation as eager settlement acceptance canidate ringers...? What was really going on in those secret backroom meetings with AstraZeneca's billion dollar legal demon dream team...? Was there ever a plan to bring any cases to trial...or was this just part of another huge SMOKE & MIRRORS campaign...?

Usually, when something doesn't quite pass the smell test; we need to start looking deeper, much deeper...That's a little hint & gift by the way; that I'm passing along to the dress suits @ the Department of Justice and the Attorney General's Office in Washington DC while they are sitting around drinking those eight dollar cups of coffee & munching on sixteen dollar muffins.

The more we dig and gather information about what has conspired, and continues to conspire in this litigation & the corrupted legal system itself....the more questions that surface which are quite disconcerting to state it as mildly as possible...We are a Nation based & grounded upon the principles of Law and Equal Justice...if those principles have been trodden upon or have been corrupted...our Nation stands today in great peril...

***If there is a disgruntled and unhappy Bailey Perrin Bailey Injured Seroquel Client who feels they have been wronged...please feel free to send along your offer packet with personal identifying information edited out to be posted on this blog***

Monday, September 12, 2011

AstraZeneca Seroquel - The Marketing of Misinformation: The name is Wayne...Wayne Macfadden AstraZeneca Senior Medical Director 2001 - 2005

cartoon brought to you via Google images
AstraZeneca Seroquel - The Marketing of Misinformation: The name is Wayne...Wayne Macfadden AstraZeneca Senior Medical Director  2001 - 2005

As a continuation to the last post: after Seroquel's former UK medical adviser John Blenkinsopp wouldn't play hide the results hardball or sign onto the Seroquel fudging the data promotional marketing tour "link here" ; AstraZeneca brought on board someone that would....that was that man about town playboy and ghost writing connoisseur Wayne MacFadden. 
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You can read all about the sordid story and background @ from Jim Edwards @bnet - astrazenecas-sex-for-studies-seroquel-scandal-did-research-chief-bias-the-science

AstraZeneca’s Sex-for-Studies Seroquel Scandal: Did Research Chief Bias the Science?

By | February 25, 2009


An AstraZeneca executive in charge of clinical research on Seroquel had sexual affairs with a researcher and a study writer, plaintiffs in a Florida lawsuit claim. BNET first wrote about the sex-for-secrets aspect of the Seroquel litigation on Feb. 17.

Now Furious Seasons blogger Philip Dawdy revealed a dynamite legal filing describing how Dr. Wayne MacFadden, AZ’s former US medical director for Seroquel and director clinical research in CNS had affairs with a clinical researcher who authored publications favorable to Seroquel, and a medical marketer who promoted Seroquel through medical publications and other means.
The plaintiffs claim the affairs may have biased the science. AZ is seeking to exclude the evidence. AZ made this statement to FS:
“AstraZeneca had no knowledge of these relationships at the time,” says Laura Woodin, an AstraZeneca spokeswoman in an email. Macfadden’s relationships with the women ran from 2002 to 2006, according to court records. “Dr. MacFadden is no longer employed with the Company.” Woodin added, “AstraZeneca has audited and stands behind the integrity of its Seroquel trial data.”
You can download the filing for yourself here. But if you can’t be bothered to read it, here’s a digest:
MacFadden became involved in a sexual relationship with an (Institute of Psychiatry) researcher who, as well as being involved in other Seroquel-related projects, participated in the clinical research and abstract preparation relating to the effectiveness of Seroquel for use in the treatment of schizophrenia. Their affair lasted from 2002 to 2006.
Sometime during 2004, while collaborating with Parexel and while still involved in a sexual relationship with the IOP researcher, MacFadden became involved in a sexual relationship with the Parexel Program Manager responsible for AstraZeneca.
The nature of their communications suggest a level of control and dependence between Macfadden and these women.

The IOP researcher suggested that Macfadden would ‘punish’ her if she even looked at studies that were favorable to Seroquel’s competitors. He actively encouraged her to conduct research the results of which would be favorable to Seroquel and AstraZeneca, and promised sexual favors in exchange for intelligence on Astrazeneca’s competitiors.
In addition to his sexual involvement with the Parexel program manager, it appears he [Macfadden] also provided her with prescription painkillers.

Macfadden agreed that sexual relationships between clinical researchers and management members of pharmaceutical companies can create bias which can affect the integrity of the science. Macfadden also acknowledged that sexual relationships can affect a person’s judgment. Although Macfadden denies that his multiple sexual relationships with these women created a conflict of interest, he in fact teased the IOP researcher about the obvious conflict of interest as he reviewed drafts of her papers on Seroquel.”
Macfadden has admitted to additional sexual affairs with a clinical researcher assistant at AstraZeneca and a clinical researcher in California also involved in the Seroquel clinical trials.
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picture via the world renowned PharmaGiles
So you might want to ask yourself?....what's so damned important, relevant, and embarrassing that AstraZeneca has their lawyers clamoring to stop these swore depositions from getting out in the public domain...I have an inkling that AstraZeneca is hoping that by working out this low ball settlement & cover up; the public will never see or hear the truth about Seroquel....think about the public safety & health issues/ramifications hiding this information may cause or will cause in the future when this drug goes generic, and is passed out like some candy after dinner mints...

On a side note...Wayne MacFadden has somehow kept his picture/photo under a mysterious veil of secrecy for many years now...if anyone has a photo of this Amorous Man about Town & former AstraZeneca Medical Director; please pass it along through email....

Why does AstraZeneca want former medical advisor John Blenkinsopp's deposition sealed?

Could the evidence be so damning that AstraZeneca wants to bury any insider discussion of the history of the making of the blockbuster antipsychotic Seroquel? Just what does AstraZeneca have to hide? could the testimony of the former medical advisor work against AstraZeneca in regard to the Seroquel diabetes lawsuits?

"the data pointed in the opposite direction"-Blenkinsopp

Listen to this AUDIO of former AstraZeneca medical advisor John Blenkinsopp


John Blenkinsopp February 2011 deposition

is court ordered to remain sealed from the public viewing to protect the confidentiality of the deposition and related exhibits in April 2011.


What do YOU think? Buried and skewed data are /could be the evidence proof that AstraZeneca is responsible for the 28,000 claimants injuries from the use of Seroquel.


Protecting the confidentiality of the deposition or hiding the evidence?

Sunday, September 11, 2011

AstraZeneca 'suppressed' drug test data on weight gain for Seroquel: former medical advisor speaks



From BBC January 2010

AstraZeneca 'suppressed' drug test data

"The marketing team sued over a drug's alleged side effects tried to suppress key data, an ex-employee has claimed.

Seroquel's former UK medical adviser told the BBC he was pressured to approve promotional material which said weight gain was not an issue.

Maker AstraZeneca, which faces fresh legal action next month, said it took concerns about its conduct seriously.

In the same programme, the British Medical Journal editor urged that the medicine licensing system be reviewed.

Dr Fiona Godlee said industry should no longer provide the evaluations of its own drugs which the licensing body considered.

'Job threat'

Thousands of patients are suing AstraZeneca in US courts, claiming the anti-psychotic drug Seroquel caused weight gain and diabetes.

The patients allege Seroquel, its second biggest selling drug worth $4.5bn (£2.7bn) a year, was marketed without adequate warning about possible side effects such as massive weight gain and the development of diabetes. However, this is denied by the company.

AstraZeneca, which is facing renewed legal action next month, said the company took concerns about its conduct seriously.

Seroquel was launched in 1997 for treating schizophrenia and later for bipolar disorder. Dr John Blenkinsopp, the company's former UK medical manager, claimed he was pressurised by the company's marketing arm to approve claims about the drug which he felt did not reflect the medical evidence.

"The clinical studies at the time of the launch of Seroquel showed patients developed significant weight gain, significant both statistically and clinically," he told the BBC's File on 4.

"They [the marketing team] came at me with a number of potential claims all of which were trying to intimate that Seroquel was not associated with weight gain - the data pointed in the opposite direction," added Dr Blenkinsopp who was speaking publicly for the first time since he left the company in 2000.

He said: "I understood where they were coming from. I had some robust discussions and exposed them to the data but that didn't seem to stop them because they were desperate for a differential advantage over one of the competitor products and they didn't have one.

"In the end I was put under quite a significant amount of pressure by the marketeers to sign off claims with regards to the lack of weight gain and I was unwilling to sign that off. The marketeers made it clear it could be career limiting for me," Dr Blenkinsopp added.

In the US the drug was marketed with claims that it would not cause weight gain. That was not done in the UK except for one advertisement, published in the British Journal of Psychiatry in April 2004."

Continue reading HERE.


LISTEN to John Blenkinsopp BBC audio interview

Friday, September 9, 2011

AstraZeneca Seroquel - 1 boring old man blog, isn't the least bit boring


I don't need to write commentary for this post...for 1 Boring Old Man Blog speaks with such knowledge, experience, insight, eloquence, and wisdom; that I will let his words speak for themselves....

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the darker side… 
 

Posted on Wednesday 7 September 2011

When one sees the size of the settlements in the civil suits against the pharmaceutical industry, the numbers [in the millions] seem impressive. Then if you look at the corporate profits [in billions], those settlements don’t look quite so large anymore. So we make the same old "cost of doing business" comment and wish for bigger settlements. Now there’s a blog I hadn’t seen before, the Seroquel Lawsuit Blog, that is looking at things from another perspective – the patient’s perspective, one case at a time – posting the letters from the law firms to the plaintiffs adding another level of complexity as the firms negotiate the settements and extract their legal fees. Stephany of the Soulful Sepulcher blog has posted a number of the documents from the site. That’s where I ran across it. It’s getting pretty complicated, as the Law firms are now going after the Seroquel Lawsuit Blog‘s anonymous blogger for posting their letters to their clients.
It’s really a discouraging story, the kind that takes its toll on your world view. The pharmaceutical company keeps the downsides of their product secret. If the injured parties succeed in a suit against them for the resulting damages, their lawyers keep their negotiations of a settlement with their clients secret. The pharmaceutical company’s lawyers and the plaintiff’s lawyers end up making a killing. The payoffs to the injured patients are fairly paltry. Then the pharmaceutical companies factor their settlements and legal fees back into their subsequent drug pricing. It’s not slightly pretty. So take a look at the Seroquel Lawsuit Blog, looking back through the older entries for an inside peek at yet another dark side to this already dark enough story…
 
As for insight into the drug Seroquel; these following links will provide you with a wealth of information

seroquel I: introduction to an “atypical”…
seroquel II: phase IIIa…
seroquel II [version 2.0]: guessing…
seroquel III: their best shot…
seroquel IV: ooching…
seroquel V: through the looking glass…
seroquel VI: the fda finale…
seroquel VI: an mid-course interlude…
seroquel VIII: sins of ommission…
seroquel IX: weighty matters…
seroquel X: matters cerebral Serebral…
seroquel XI: through a glass darkly…
seroquel XII: an opinionated postscript…
and the series continues on.......
selling seroquel I: background…
selling seroquel II: into the fray…
selling seroquel III: the data factories…
selling seroquel IV: way off label…
selling seroquel: a mid-winter break…
selling seroquel V: driving the brand…
selling seroquel VI: claims…
selling seroquel VII: indication sprawl…
selling seroquel VIII: CRO-Charts…
contents of an empty mind……
the clinical research industry: time-to-market and beyond…
the clinical research industry: the CRCs…
we interrupt this program for… gulp…
the clinical research industry: the cro running in the background…
the clinical research industry: an invisible empire…
the clinical reasearch industry: the ‘atypical’ decade…
patent medicines…
Seroquel XR: an extended release…
supercharged placebos…
atypical augmentation: statistical but irrelevant… 
and this week...
the system…